Traditional face to face modality
know the drugs directly and indirectly related with the practice of dentistry and understand the implications of drug therapy of systemic diseases on dental treatments.
student has to know the drugs directly and indirectly related with the practice of dentistry and understand the implications of drug therapy of systemic diseases on dental treatments.
• Francesco Rossi, Vincenzo Cuomo, Carlo Riccardi - Farmacologia. Principi di base e applicazioni terapeutiche. Autori: - Editore: Minerva Medica, 2011
• Rang H.P., Dale M.M., Ritter J.M. – Farmacologia – Casa Editrice Ambrosiana, Milano,1998.
• Goodman & Gilman - Le basi farmacologiche della terapia - Editore: ZANICHELLI
Pharmacodynamics: Mechanisms of action of drugs. Pharmacokinetics: general concepts relating to the physical-chemical properties of the drugs absorption, distribution, metabolism, elimination, pharmacokinetic parameters. Pharmaceutical Preparations. Diagnostic drugs. Factors of variability of drug response: factors related to the drug, factors inherent to the patient, drug interactions. Abnormal responses to drug delivery: idiosyncratic reactions, allergic reactions
CELLULAR AND MOLECULAR PHARMACOLOGY:
Receptors and signal transduction. Classes of receptors: membrane receptors, intracellular receptors, modulation of receptor responses. The ionic transport: ion channels; pumps. Transmission systems: catecholaminergic transmission; cholinergic transmission; serotonergic transmission; neurotransmission mediated by amino acid inhibitors; neurotransmission mediated by excitatory amino acids; opioid peptides; neuropeptides; transmission histamine; pharmacology of nitric oxide; metabolism of arachidonic acid.
DRUGS OF THE NERVOUS SYSTEM:
Drugs for the treatment of anxiety and insomnia. anxiety disorders; benzodiazepines; non-benzodiazepine anxiolytics; non-benzodiazepine hypnotics; Drugs for the treatment of affective disorders: major depression; bipolar disorder; Drugs for the treatment of epilepsies: pharmacodynamics; the major antiepileptic drugs; other antiepileptic drugs; Drugs for the treatment of Parkinson's levodopa; dopamine agonists; inhibitors of catechol-O-methyl-transferase; monoamine oxidase inhibitors; anticholinergics; amantadine; Drugs in the treatment of Alzheimer's dementia: therapeutic approaches for Alzheimer's dementia; Medications for the treatment of pain: non-opioid analgesics; opioid analgesics; Drugs of general anesthesia: inhalational anesthetics; intravenous anesthetics; opioid analgesics; Local anesthetics: historical outline; classification, physical and chemical properties and structure-activity relationship; mechanism of action; pharmacokinetics; adverse reactions; drug interactions; indications.
DRUGS OF THE CARDIOVASCULAR SYSTEM, BLOOD AND KIDNEY:
Antihypertensive drugs: regulation of blood pressure; goals of treatment and choice of antihypertensive drugs; targets of antihypertensive drugs; diuretics; drugs inhibiting the renin-angiotensin-aldosterone system; the adrenergic neuron blocking agents and reserpine; α2-adrenergic receptor agonists (central α agonists); αı-adrenergic receptor antagonists (α-blockers); β-adrenergic receptor antagonists (β-blockers); calcium channel blockers (CCBs); direct vasodilators; Drugs for the treatment of ischemic heart disease, antianginal drugs; drugs for the treatment of acute coronary syndromes; Drugs of heart failure, digitalis; no inotropic digitalis; Blood, blood components and artificial substitutes: functions of blood and its components; artificial blood substitutes; Drugs of hemostasis: antiplatelet drugs; coagulants and anticoagulants; fibrinolytic and anti-fibrinolytic drugs.
DRUGS OF THE RESPIRATORY SYSTEM:
Adjusting the tone bronchomotor: cholinergic system; adrenergic system; system not adrenergic non cholinergic (NANC); Factors and mediators of inflammation: pro-inflammatory cytokines; anti-inflammatory cytokines; chemokines; Drugs for the treatment of bronchial asthma: cortisone; bronchodilators; cromones; antieucotrieni;
DRUGS OF THE DIGESTIVE SYSTEM:
Inhibitors of acid secretion, gastric mucosal protective and anti-ulcer, antacids; histamine H2-receptor antagonists; muscarinic receptor antagonists; proton pump inhibitors; receptor antagonists of gastrin; somatostatin; prostaglandin analogues; gastroprottetivi other drugs; drugs for the eradication of Helicobacter pylori.
DRUGS OF INFLAMMATION:
Nonsteroidal antiinflammatory drugs: pharmacodynamics; pharmacokinetics; indications; adverse effects and interactions with other drugs; contraindications; Steroidal anti-inflammatory drugs: natural corticosteroids; pharmacodynamics; p